Parkinson Disease is disorder of neurological movement which eventually leads to disability because of decreased level of dopamine . Pathophysiology:- Clinical manifestations:- Cardinal signs of Parkinson Disease are :- 1. Tremor 2. Rigidity 3. Bradykinesia 4. Postural instability 5. Uncontrolled sweating 6. Drooling 7. Paroxysmal flushing 8. Orthostatic hypothension 9. Gastric retention 10. Urinary retention 11. Constipation 12. Sexual dysfunction 13. Anxiety 14. Dysphagia 15. Dementia 16. Stress Subtypes of Parkinson Disease:- 1. Tremor dominant - symptoms are absent 2. Nontremor dominant - postural instability - rigidity - bradykinesia Diagnosis:- 1. Patient history 2. Presences of cardinal signs 3. Neurological examination 4. Diagnosis confirmed with postive response of levodopa ( artificial dopamine ) 5. Single Photon emission computer tomography Management :- Treatment is to directed towards controlling of symptoms and maintenance of...
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